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Aspirin and Diphenhydramine

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • U.S. Brand Names: Alka-Seltzer® P.M. [OTC];Bayer® PM [OTC]
    • Pharmacologic Category: Analgesic, Miscellaneous

    Uses
    • This medicine is used to treat sleep disorders.
    • This medicine is used to relieve pain.
    • Aspirin blocks production and release of chemicals that cause pain and inflammation.
    • Diphenhydramine calms the brain.

    Dosing

    How to take

    • Take this medicine 30-60 minutes before bedtime if using for sleep. Do not take for more than 2 weeks in a row.
    • Dissolve effervescent tablet in 1/2 cup of water. Do not swallow whole.
    • Swallow caplets whole. Do not chew, break, or crush.
    • Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

    Missed Dose

    • Take a missed dose as soon as possible.
    • If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
    • Do not take a double dose or extra doses.
    • Many times this medicine is taken on an as needed basis.

    Storage

    • Store at room temperature.
    • Protect from moisture. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • Children and teenagers should not use aspirin for flu symptoms or chickenpox.
    • This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.

    Avoid

    • Do not give this medicine to a child younger than 12 years of age.
    • If you have an allergy to aspirin, diphenhydramine, or any other part of this medicine.
    • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
    • If you are more than 24 weeks pregnant.
    • If you are breast-feeding.

    Precautions

    • If you have glaucoma, talk with healthcare provider.
    • If you have lung disease, talk with healthcare provider. You may be more sensitive to this medicine.
    • If you are a male with problems urinating, talk with healthcare provider.
    • If you have had an ulcer or bleeding from your stomach or intestines, talk with healthcare provider.
    • If you have PKU, talk with healthcare provider. Some products do contain phenylalanine.
    • If you start on a low salt diet, tell healthcare provider. It will change the way your body handles the lithium.
    • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
    • Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.
    • You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.
    • You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
    • Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions.
    • Tell healthcare provider if you are pregnant or plan on getting pregnant.
    • Use birth control that you can trust to prevent pregnancy while taking this medicine.

    Side Effects

    • Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.
    • Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
    • Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Belly pain or heartburn.
    • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

    Monitoring

    • Change in condition being treated. Is it better, worse, or about the same?
    • Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.

    Contact a healthcare provider

    • If you suspect an overdose, call your local poison control center or emergency department immediately.
    • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
    • Difficulty breathing.
    • Significant change in thinking clearly and logically.
    • Ringing in ears.
    • Black, tarry, or bloody stools.
    • Blood in the urine.
    • Unusual bruising or bleeding.
    • Unable to pass urine.
    • Feeling extremely tired or weak.
    • Any rash.
    • No improvement in condition or feeling worse.

    General Statements

    • If you have a life-threatening allergy, wear allergy identification at all times.
    • Do not share your medicine with others and do not take anyone else's medicine.
    • Keep all medicine out of the reach of children and pets.
    • Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada return any unused drugs back to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th for more facts about the right way to get rid of unused drugs.
    • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
    • Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
    • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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