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Ketoconazole (Systemic)

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Canadian Brand Names: Apo-Ketoconazole®;Novo-Ketoconazole
    • Pharmacologic Category: Antifungal Agent, Oral

    Uses
    • It is used to stop or treat yeast infections.
    • It is used to treat prostate cancer.
    • Ketoconazole works to harm the yeast and fight the infection.
    • It may lower testosterone levels.

    Dosing

    How to take

    • To gain the most benefit, do not miss doses.
    • Use as told, even if feeling better.
    • Take this drug at the same time of day.
    • Take this drug with food.
    • There is a liquid (suspension) if you cannot swallow pills. Shake well before use.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to time for the next dose, skip the missed dose and return to your normal time.
    • Do not take two doses or extra doses.
    • Do not change dose or stop drug. Talk with doctor.

    Storage

    • Store at room temperature.
    • Protect tablets from water. Do not store in a bathroom or kitchen.
    • Store liquid (suspension) at room temperature. Throw away any part not used after 2 months.

    Safety



    Warnings

    • This medicine may cause severe liver damage.
    • Unsafe reactions may happen. This drug cannot be taken while you are taking certain other drugs. Check all the drugs you are taking with your doctor.

    Avoid

    • If you have an allergy to ketoconazole or any other part of this drug.
    • Tell doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs involved.
    • If you have a yeast infection of the brain.

    Precautions

    • If you have liver disease, talk with doctor.
    • Check drugs with doctor. This drug may not mix well with other drugs.
    • Do not take antacids or sucralfate within 2 hours of this drug.
    • Avoid grapefruit and grapefruit juice.
    • Avoid alcohol (includes wine, beer, and liquor).
    • Tell doctor if you are pregnant or plan on getting pregnant.
    • Tell doctor if you are breast-feeding.

    Side Effects

    • Belly pain.
    • Upset stomach or throwing up. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools.
    • Liver damage can rarely happen.

    Monitoring

    • Change in health problem being treated. Is it better, worse, or about the same?

    Contact a healthcare provider

    • If you suspect an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad belly pain.
    • Very upset stomach or throwing up.
    • Very bad loose stools.
    • Not able to eat.
    • Dark urine or yellow skin or eyes.
    • Feeling very tired or weak.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada return any unused drugs back to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th for more facts about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, supplements, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for health help about side effects. You may also call the FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
    • Talk with doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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