Table of Contents > Drug > Azacitidine Print

Azacitidine

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Vidaza®
    • Pharmacologic Category: Antineoplastic Agent, DNA Methylation Inhibitor

    Uses
    • It is used to treat some types of leukemias and bone marrow problems.
    • Azacitidine harms cancer cells causing their death.

    Dosing

    How to take

    • It is given as a shot into the fatty part of the skin.
    • It is given as a shot into a vein over a period of time.

    Missed Dose

    • Call your doctor for an office visit.

    Storage

    • This drug will be given to you in a hospital or doctor's office. You will not store it at home.

    Safety



    Warnings

    • Unsafe side effects may happen. This drug cannot be taken while you are taking some other drugs. Check all the drugs you are taking with your doctor.

    Avoid

    • If you have an allergy to azacitidine or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have liver tumors.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.

    Precautions

    • Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of a very bad infection or make the vaccine not work as well.
    • If you have kidney disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • Have your blood work checked often. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Take good care of your teeth. See a dentist often.
    • Use 2 kinds of birth control that you can trust 1 month before care begins, during care, and for at least 1 month after care ends.
    • If you are a man and have sex, protect your partner from pregnancy. Use 2 kinds of birth control that you can trust 1 month before care begins, during care, and for at least 1 month after care ends.

    Side Effects

    • Anemia, low white blood cell count, and low platelet count.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Chance of getting an infection. Avoid people with infections, colds, or flu.
    • Fever.
    • Headache.
    • Feeling tired or weak.
    • Irritation where the shot is given.
    • Swelling in the arms or legs.
    • Loose stools.
    • Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Very bad dizziness or passing out.
    • Very upset stomach or throwing up.
    • Very hard stools (constipation).
    • Very loose stools.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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