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Mefloquine

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Canadian Brand Names: Apo-Mefloquine®;Lariam®
    • Pharmacologic Category: Antimalarial Agent

    Uses
    • It is used to stop or treat malaria.
    • Mefloquine protects you from getting malaria.
    • It works to harm the bacteria and fight the infection.

    Dosing

    How to take

    • This drug should be started before travel to the high risk area. Keep using after leaving the area.
    • To gain the most benefit, do not miss doses.
    • Use as told, to stop malaria.
    • Take this drug with food.
    • Take with a full glass of water.
    • To treat malaria, take a single dose. To keep the infection from coming back, take this drug with some other antibiotic.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If you miss a dose before leaving for your trip, call doctor to find out what to do.
    • If it is close to time for the next dose, skip the missed dose and return to your normal time.
    • Do not take two doses or extra doses.

    Storage

    • Store at room temperature.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • Unsafe reactions may happen. This drug cannot be taken while you are taking certain other drugs. Check all the drugs you are taking with your doctor.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to mefloquine or any other part of this drug.
    • If you have an allergy to quinidine or quinine.
    • Tell doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs involved.
    • If you have any of these health problems: Anxiety, low mood (depression), psychosis, or seizures.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.

    Precautions

    • Have patient safety card with you at all times.
    • If you have liver disease, talk with doctor.
    • If you have heart disease, talk with doctor.
    • Other protective measures are needed along with this drug including using screens, bed netting, insect repellent (10% to 35% DEET), and permethrin spray on clothing and nets. Avoid spraying most insect repellents on children. Lower evening and night-time outdoor activity.
    • Check all drugs you are taking with your doctor. This drug may not mix well with certain other drugs.
    • You may not be alert. Avoid driving, doing other tasks or activities until you see how this drug affects you.
    • Avoid alcohol (includes wine, beer, and liquor) or other drugs and natural products that slow your actions and reactions.
    • Avoid grapefruit and grapefruit juice.
    • Use birth control that you can trust to stop pregnancy while taking this drug.

    Side Effects

    • Treatment of malaria:
    • Headache.
    • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving, doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
    • Upset stomach or throwing up. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Stopping malaria:
    • Feeling dizzy. Rise slowly over a few minutes from sitting or lying position. Be careful climbing.
    • Upset stomach or throwing up. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Hallucinations.
    • Not able to sleep.
    • Bad dreams.
    • Psychosis can rarely happen.
    • Seizures can rarely happen.

    Monitoring

    • Change in health problem being treated. Is it better, worse, or about the same?

    Contact a healthcare provider

    • If you suspect an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, not normal thinking, anxiety, or lack of interest in life.
    • Chest pain or pressure or fast heartbeat.
    • Very bad dizziness or passing out.
    • Trouble breathing.
    • Flu-like signs.
    • Very nervous and excitable.
    • Very upset stomach or throwing up.
    • Big change in thinking clearly and with logic.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada return any unused drugs back to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th for more facts about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, supplements, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for health help about side effects. You may also call the FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
    • Talk with doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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