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Related terms
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    Related terms
    • U.S. Brand Names: MetozolvT ODT;Reglan®
    • Canadian Brand Names: Apo-Metoclop®;Metoclopramide Hydrochloride Injection;Metoclopramide Omega;Nu-Metoclopramide;PMS-Metoclopramide
    • Mexican Brand Names: Carnotprim;Dirpasid;Meclomid;Plasil;Polcotec
    • Pharmacologic Category: Antiemetic;Gastrointestinal Agent, Prokinetic

    • It is used in patients getting tube feedings who have high residuals.
    • It is used to treat heartburn.
    • It is used to stop or treat upset stomach and throwing up.
    • It is used to treat gastroesophageal reflux disease.
    • Metoclopramide raises gastric emptying of food and lowers signs of upset stomach, throwing up, heartburn, and fullness.


    How to take

    • Take 30 minutes before meals and at bedtime.
    • Oral-disintegrating tablet: Place on tongue and let dissolve. Water is not needed. Do not swallow whole. Do not chew, break, or crush.
    • There is a liquid (solution, syrup) if you cannot swallow pills.
    • Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after this drug is given.
    • Injection:
    • It is given as a shot into a muscle or vein.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to time for the next dose, skip the missed dose and return to your normal time.
    • Do not take two doses or extra doses.
    • Many times this drug is given on an as needed basis.


    • Store at room temperature.
    • Protect tablets from water. Do not store in a bathroom or kitchen.
    • The injection will be given to you in a doctor office setting. You will not store it at home.



    • This drug may cause muscle movements that you cannot control. Talk with doctor.
    • Unsafe reactions may happen. This drug cannot be taken while you are taking certain other drugs. Check all the drugs you are taking with your doctor.
    • Please read the medication guide.


    • If you have an allergy to metoclopramide or any other part of this drug.
    • Tell doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs involved.
    • If you have any of these health problems: GI (gastrointestinal) bleeding, hole in the GI tract, bowel block, pheochromocytoma, or seizures.


    • If you have high blood sugar (diabetes), talk with doctor.
    • If you have heart disease, talk with doctor.
    • If you have kidney disease, talk with doctor.
    • If you have mental illness, talk with doctor.
    • If you have Parkinson's disease, talk with doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with certain other drugs.
    • Avoid alcohol, quit smoking, elevate head of the bed, avoid large meals before bed, lose weight, and avoid fatty foods, chocolate, caffeine, or citrus.
    • You may not be alert. Avoid driving, doing other tasks or activities until you see how this drug affects you.
    • Tell doctor if you are pregnant or plan on getting pregnant.
    • Tell doctor if you are breast-feeding.

    Side Effects

    • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving, doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
    • Headache.
    • Belly pain.
    • Loose stools.
    • Not able to calm down.
    • Not able to sleep.


    • Change in health problem being treated. Is it better, worse, or about the same?

    Contact a healthcare provider

    • If you suspect an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • If you are planning to harm yourself or the want to harm yourself gets worse.
    • Fast heartbeat.
    • Very bad dizziness or passing out.
    • Twitching.
    • Big change in thinking clearly and with logic.
    • Shakiness, trouble moving around, or stiffness.
    • Very bad loose stools.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada return any unused drugs back to the pharmacy. Also, visit for more facts about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, supplements, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for health help about side effects. You may also call the FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
    • Talk with doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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