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Tirofiban

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Aggrastat®
    • Brand Names: Canada: Aggrastat®
    • Mexican Brand Names: Agrastat
    • Pharmacologic Category: Antiplatelet Agent, Glycoprotein IIb/IIIa Inhibitor

    Uses
    • It is used during a heart treatment to protect the arteries.
    • It is used to lower the number of heart attacks in patients who have unstable angina or mild heart attacks.
    • Tirofiban stops platelets from getting sticky and clumping.

    Dosing

    How to take

    • It is given as a shot into a vein over a period of time.

    Missed Dose

    • Call your doctor to find out what to do.

    Storage

    • This drug will be given to you in a hospital or doctor's office. You will not store it at home.

    Safety



    Avoid

    • If you have an allergy to tirofiban or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Aneurysm, arteriovenous malformations, bleeding problems, brain tumor, low platelet count, recent surgery or injury, stroke, or very high blood pressure.
    • If you are breast-feeding.

    Precautions

    • If you are 65 or older, use this drug with care. You could have more side effects.
    • If you have kidney disease, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Tell your doctor if you are pregnant or plan on getting pregnant.

    Side Effects

    • Bleeding problems.
    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Irritation where the shot is given.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad dizziness or passing out.
    • A fall or crash when you hit your head. Talk with your doctor even if you feel fine.
    • Change in thinking clearly and with logic.
    • Very bad headache.
    • Any bruising or bleeding.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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